The ability to accurately determining the three dimensional structure of a molecule is highly relevant in all fields of chemistry. Rotational spectroscopy is a well-known and powerful tool for determining the structure of gas phase molecules, and with the development of chirped-pulse Fourier transform microwave (CP-FTMW) spectroscopy, data acquisition times are reduced immensely, allowing for a broader set of applications. During my talk I will use two examples to demonstrate the utility of using a multiplexed approach by combining broadband microwave spectroscopy with optical methods. First, a combination of broadband microwave spectroscopy and VUV photoionization time-of-flight mass spectrometry was used to acquire the pure rotational spectrum of phenoxy radical. [1,2] Second, the advancements towards maximizing state-specific enantiomeric enrichment for highly sensitive chiral analysis will be described. These are made possible using a joint high-resolution laser induced fluorescence and microwave spectroscopy instrument. 
 Fritz, S. M., Hays, B. M., Hernandez-Castillo, A. O., Abeysekera, C. & Zwier, T. S. Rev Sci Instrum 89, 093101, (2018).
 Hernandez-Castillo, A. O., Abeysekera, C., Stanton, J. F. & Zwier, T. S. J Phys Chem Lett 10, 2919-2923, (2019).
 Hernandez-Castillo, A. O. et al. Phys Chem Chem Phys, (2021) Advance Article (doi.org/10.1039/D0CP06170K).