|Title||Carbohydrate-bearing 3-hydroxy-4-pyridinonato complexes of gallium(III) and indium(III)|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Green, DE, Ferreira, CL, Stick, RV, Patrick, BO, Adam, MJ, Orvig, C|
|Type of Article||Article|
|Keywords||aluminum, ANALOGS, CITRATE, GLUCOSE, INVIVO, SYSTEM, TC-99M|
Gallium and indium complexes with pendant carbohydrates have been prepared and examined for their potential as radiopharmaceuticals. Carbohydrate-bearing 3-hydroxy-4-pyridinone ligand precursors and their tris(ligand)gallium(III) and -indium(III) complexes were synthesized and characterized by mass spectrometry, elemental analysis, and H-1 and C-13 NMR spectroscopy, and in the case of one intermediate, by X-ray crystallography. With three equivalents of ligand, neutral complexes formed with the bidentate hydroxypyridinone moiety complexing the gallium(III) and indium(III) metal centers.
|URL||<Go to ISI>://000233393800036|