Research & Teaching Faculty

Default Header Image

Cation-Complexation Behavior of Template-Assembled Synthetic G-Quartets

TitleCation-Complexation Behavior of Template-Assembled Synthetic G-Quartets
Publication TypeJournal Article
Year of Publication2009
AuthorsNikan, M, Sherman, JC
JournalJournal of Organic Chemistry
Volume74
Pagination5211-5218
Date PublishedAug
Type of ArticleArticle
ISBN Number0022-3263
KeywordsALKALI-METAL CATIONS, CROWN-ETHERS, DEOXYGUANOSINE, DIFFRACTION, DIFFUSION NMR-SPECTROSCOPY, DNA, GUANOSINE, ION-BINDING, LIPOPHILIC G-QUADRUPLEX, RAY FIBER, SODIUM
Abstract

We report the preparation and solution study of a set of template-assembled synthetic G-quartets (TASQs) bound to different cations. These G-quartet baskets effectively extract cations of different sizes and valencies, They form isolated G-quartets with small cations such as Na+ and Sr2+, and dimeric assemblies with larger cations such as Cs+. Their structures were determined by using H-1 NMR spectroscopy, and their sizes were evaluated by using a series of pulsed-field gradient NMR experiments. The effect of anion has been studied, and the cation selectivities have been investigated by a series of competition experiments.

URL<Go to ISI>://000268480300011