|Title||Molecular mechanics-assisted crystal engineering of solid state photoreactions: application to the Yang photocyclization of alpha-1-norbornylacetophenone derivatives|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Botoshansky, M, Braga, D, Kaftory, M, Maini, L, Patrick, BO, Scheffer, JR, Wang, KY|
|Type of Article||Article|
|Keywords||ASYMMETRIC INDUCTION, crystal engineering, GEOMETRIC REQUIREMENTS, II REACTION, ionic chiral auxiliaries, REACTIVITY, solid state photochemistry, X-RAY CRYSTALLOGRAPHY, Yang photocyclization|
Based on molecular mechanics, Yang photocyclization of alpha-1-norbornylacetophenone derivatives in the crystalline state was engineered through methylation adjacent to the carbonyl group, thus changing the conformation in the crystal and leading to enhanced diastereo- and enantioselectivity. (C) 2004 Elsevier Ltd. All rights reserved.
|URL||<Go to ISI>://000226846800021|