@article {2789,
	title = {POTENTIAL TC-99M RADIOPHARMACEUTICALS FOR RENAL IMAGING - TRIS(N-SUBSTITUTED-3-HYDROXY-2-METHYL-4-PYRIDINONATO)TECHNETIUM(IV) CATIONS},
	journal = {Nuclear Medicine and Biology},
	volume = {20},
	number = {7},
	year = {1993},
	note = {ISI Document Delivery No.: LY636Times Cited: 9Cited Reference Count: 21},
	month = {Oct},
	pages = {857-863},
	type = {Article},
	abstract = {A series of monocationic complexes of N-substituted-3-hydroxy-2-methyl-4-pyridinones labeled with technetium(IV)-99m have been evaluated in vivo as potential radiopharmaceuticals. The pyridinones have different substituents at the ring nitrogen atom: ethyl, i-propyl, i-butyl, benzyl, phenyl, p-methoxyphenyl, 3-butoxypropyl and cyclohexyl. Biodistribution studies of the Tc-99m complexes have been carried out in rabbits and mice. High kidney uptake and retention of the radionuclide has been shown in rabbits and mice with the cationic complexes of 3-hydroxy-1-(p-methoxyphenyl)-2-methyl-4-pyridinone and 1-(cyclohexyl)-3-hydroxy-2-methyl-4-pyridinone. These (TcL3+)-Tc-99m compounds appear to be morphologic renal agents.},
	keywords = {3-HYDROXY-4-PYRIDINONES, aluminum, CHEMISTRY, COMPLEXES, gallium, INVIVO},
	isbn = {0883-2897},
	url = {<Go to ISI>://A1993LY63600007},
	author = {Edwards, D. S. and Liu, S. N. and Lyster, D. M. and Poirier, M. J. and Vo, C. and Webb, G. A. and Zhang, Z. H. and Orvig, Chris}
}
