@article { ISI:000238563300045, title = {Fine tuning of beta-glucosidase inhibitory activity in the 2,5-dideoxy-2,5-imino-D-mannitol (DMDP) system}, journal = {CARBOHYDRATE RESEARCH}, volume = {341}, number = {10}, year = {2006}, month = {JUL 24}, pages = {1717-1722}, abstract = {Based on our extensive studies of D-glucosidase inhibiting 2,5-dideoxy-2,5-imino-D-mannitol derivatives, we have been trying to create a series of fluorescent derivatives with a view to an {\textquoteleft}inhibitory activity ruler{\textquoteright} based on competitive displacement reactions of non-fluorescent inhibitors by fluorescent ones and vice versa, which can be performed and followed in microtiter plates or on-chips. Thus, a set of compounds was assembled with K-i values between 2 nM and 1 mu M against Agrobacterium sp. beta-glucosidase. (c) 2006 Elsevier Ltd. All rights reserved.}, issn = {0008-6215}, doi = {10.1016/j.carres.2006.03.010}, author = {Wrodnigg, Tanja M. and Stuetz, Arnold E. and Tarling, Chris A. and Withers, Stephen G.} }