@article { ISI:000279258800018, title = {Synthesis and biological evaluation of novel biotin-iminoalditol conjugates}, journal = {BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS}, volume = {20}, number = {14}, year = {2010}, month = {JUL 15}, pages = {4077-4079}, abstract = {Biotin-iminosugar conjugates of different configuration such as D-gluco, D-galacto, L-ido as well as a furanoid representative in the D-manno configuration have been synthesised and exhibit powerful inhibition of beta-glucosidase from Agrobacterium sp. with K(i) values in the range of the respective parent compounds. Such molecular probes have potential for activity-based protein pro. ling taking advantage of the biotin-(strept)avidin interaction. (C) 2010 Elsevier Ltd. All rights reserved.}, issn = {0960-894X}, doi = {10.1016/j.bmcl.2010.05.084}, author = {Pototschnig, Gerit and De Csaky, Christian Morales and Burke, Jose R. Montenegro and Schitter, Georg and Stuetz, Arnold E. and Tarling, Chris A. and Withers, Stephen G. and Wrodnigg, Tanja M.} }