@article { ISI:000333443800009,
	title = {Improved separation of the curcuminoids, syntheses of their rare earth complexes, and studies of potential antiosteoporotic activity},
	journal = {J. Inorg. Biochem.},
	volume = {132},
	number = {SI},
	year = {2014},
	month = {MAR},
	pages = {52-58},
	abstract = {<p>The first reported homogenous rare earth curcumin (HCurc; ((1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5-dione)) complexes with the formula ML3, where M3+ is Eu(III), Gd(III) or Lu(III), were synthesized and characterized by mass spectrometry, infrared spectroscopy and, in the case of the lutetium complex, H-1 NMR spectroscopy. Most importantly an improved separation of the three curcuminoids, HCurc, HDMC ((lE,6E)-1-(4-hydroxy-3-methoxypheny1)-7-(4-hydroxyphenyl)hepta-1,6-dien e-3,5-dione) and HBDMC ((1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione) was realized using a combination of normal-phase column and phosphate-impregnated preparative-thin layer chromatographies. The toxicities of the metal curcumin complexes and ligands were investigated in MG-63 cells, an osteoblast-like cell line, for potential activity as antiosteoporotic agents. (c) 2013 Elsevier Inc. All rights reserved.</p>},
	issn = {0162-0134},
	doi = {10.1016/j.jinorgbio.2013.12.004},
	author = {Mawani, Yasmin and Orvig, Chris}
}
