@article {23234,
	title = {Deuteration of Aromatic Rings under Very Mild Conditions through Keto-Enamine Tautomeric Amplification},
	journal = {Journal of Organic Chemistry},
	volume = {80},
	number = {10},
	year = {2015},
	note = {Times Cited: 0 0},
	pages = {5144-5150},
	abstract = {We have discovered a surprising, mild method for deuteration of select aromatic compounds that is facilitated by a keto-enamine tautomeric intermediate: The mechanism of the reaction has been studied using kinetics experiments and detailed computational analysis. It was found that a chain of water molecules has a substantial role in lowering the activation barrier to the tautomerization-enhanced deuteration reaction. Our results demonstrate that tautomeric forms of aromatic molecules can be exploited to bring about enhanced reactivity.},
	issn = {0022-3263},
	doi = {10.1021/acs.joc.5b00539},
	url = {<Go to ISI>://WOS:000354908500032},
	author = {Mehr, S. Hessam M. and Fukuyama, Katsuya and Bishop, Stephanie and Lelj, Francesco and MacLachlan, Mark J.}
}
