@article {C3MD00328K,
	title = {A new 18F-heteroaryltrifluoroborate radio-prosthetic with greatly enhanced stability that is labelled by 18F-19F-isotope exchange in good yield at high specific activity},
	journal = {Med. Chem. Commun.},
	volume = {5},
	year = {2014},
	pages = {171-179},
	publisher = {The Royal Society of Chemistry},
	abstract = {An 18F-heteroaryltrifluoroborate was designed as a novel radioprosthetic for PET imaging. The stability of the new prosthetic was confirmed using 19F-NMR spectroscopy: the solvolytic half-life was measured to be >16 000 min. Conjugation to RGD gave a stable radiotracer precursor for kit-like labeling by 18F-19F isotope exchange in 15 min. The total radiosynthetic procedure including HPLC purification requires <45 min. A plasma stability assay showed negligible defluoridation following 150 min and stability is corroborated by in vivo imaging showing minimal bone uptake. With Curie levels of 18F-fluoride{,} yields of 20\% and specific activities as high as 3 Ci [small mu ]mol-1 (110 GBq [small mu ]mol-1) are achieved (n = 3).},
	doi = {10.1039/C3MD00328K},
	url = {http://dx.doi.org/10.1039/C3MD00328K},
	author = {Liu, Z. and Hundal-Jabal, N. and Wong, M. and Yapp, D. and Lin, K.-S. and Benard, F. and Perrin, D. M.}
}
