@article {Mjos2016280,
	title = {Synthesis, characterization, and evaluation of the antimicrobial potential of copper(II) coordination complexes with quinolone and p-xylenyl-linked quinolone ligands},
	journal = {J. Inorg. Biochem.},
	volume = {162},
	year = {2016},
	pages = {280 - 285},
	abstract = {<p>Abstract The antimicrobial properties of copper have been known to mankind since the ancient times. In a coordination chemistry approach to develop novel antimicrobial agents, the quinolone antimicrobial agents ciprofloxacin (Hcipro) and pipemidic acid (Hpia), as well as dimers thereof (piperazinyl-linked with a p-xylenyl moiety) were complexed with copper(II). The synthesis and antimicrobial evaluation of bis(ciprofloxacino)copper(II) [Cu(cipro)2], bis(pipemido)copper(II) [Cu(pia)2], and the corresponding dimer complexes, [Cu2(ciproXcipro)2] and [Cu2(piaXpia)2], are reported. No combinational or synergistic effect between copper(II) and the respective quinolone ligands was observed in vitro.</p>},
	keywords = {p-xylenyl-crosslinkage},
	issn = {0162-0134},
	doi = {http://dx.doi.org/10.1016/j.jinorgbio.2016.02.026},
	url = {http://www.sciencedirect.com/science/article/pii/S0162013416300526},
	author = {Katja Dralle Mjos and Elena Polishchuk and Michael J. Abrams and Chris Orvig}
}
