@article {KURAKINA2021,
	title = {Improved separation scheme for 44Sc produced by irradiation of natCa targets with 12.8 MeV protons},
	journal = {Nucl. Med. Biol.},
	volume = {104-105},
	year = {2022},
	month = {11/2021},
	pages = {22-27},
	abstract = {<p>Introduction 44Sc is of great interest as a positron emission tomography (PET) radionuclide due to its suitable nuclear characteristics: Eβ+max = 1.47MeV, branching ratio 94.3\% and convenient half-life of 3.97 h. Here, 44Sc was produced via the widely used reaction 44Ca (p,n)44Sc using natural calcium as a target. Methods The irradiation was performed at TRIUMF using the 13 MeV cyclotron. The separation consisted of a combination of DGA branched resin and Dowex 50Wx8 (200\&ndash;400 mesh). The distribution coefficients of Sc3+ on Dowex 50Wx8 (NH4+ form, 200\&ndash;400 mesh) with ammonium α-hydroxyisobutyrate (pH = 4.8) medium were determined in this study. Results and conclusion The tested scheme allows both a reliable separation of 44Sc from the target material as well as from the other competitive metals and a final fraction with high specific activity. The achieved radiochemical yield was 95 \&plusmn; 3\%.</p>},
	keywords = {Cation exchange, DGA, Irradiation of natural Ca, Radiochemical separation, radiolabeling, Sc},
	issn = {0969-8051},
	doi = {https://doi.org/10.1016/j.nucmedbio.2021.11.002},
	url = {https://www.sciencedirect.com/science/article/pii/S0969805121005102},
	author = {E.S. Kurakina and L. Wharton and C. Hoehr and C. Orvig and E.P. Magomedbekov and D. Filosofov and V. Radchenko}
}
