@article {38727,
	title = {A simple and automated method for 161Tb purification and ICP-MS analysis of 161Tb},
	journal = {EJNMMI Radiopharmacy and Chemistry},
	volume = {7},
	year = {2022},
	abstract = {<p><sup>161</sup>Tb is a radiolanthanide with the potential to replace <sup>177</sup>Lu in targeted radionuclide therapy. <sup>161</sup>Tb is produced via the neutron irradiation of [160Gd]Gd2O3 targets, and must be purified from <sup>160</sup>Gd and the decay product <sup>161</sup>Dy prior to use. Established purification methods require complex conditions or high-pressure ion chromatography (HPIC) which are inconvenient to introduce in a broad user community. In this study, <sup>161</sup>Tb was successfully purified by a semi-automated TRASIS system using a combination of TrisKem extraction resins. The resulting product performed well in radiolabelling and in vivo experiments. An ICP-MS method to analyze the radioactive product was developed. Combined with gamma spectroscopy, this method allows the purity of <sup>161</sup>Tb being assessed before the decay of the product, providing a useful tool for quality control.</p>},
	url = {https://ejnmmipharmchem.springeropen.com/articles/10.1186/s41181-022-00183-y},
	author = {S. W. McNeil and M. Van de Voorde and C. Zhang and M. Ooms and F. B{\'e}nard and V. Radchenko and H. Yang}
}
