@article {2008,
	title = {Tissue uptake, mortality, and sublethal effects of monomethylarsonic acid (MMA(V)) in nestling zebra finches (Taeniopygia guttata)},
	journal = {Journal of Toxicology and Environmental Health-Part a-Current Issues},
	volume = {71},
	number = {6},
	year = {2008},
	note = {Albert, Courtney Williams, Tony D. Morrissey, Christy A. Lai, Vivian W. -M. Cullen, William R. Elliott, John E.},
	pages = {353-360},
	abstract = {Monosodium methanearsonate (MSMA), an arsenic-based pesticide, has been used since the mid 1980s in attempts to suppress mountain pine beetle (Dendroctonus ponderosae) outbreaks in British Columbia, Canada. It was previously shown that cavity nesting forest birds forage and breed in MSMA-treated pine stands. The present study was designed to investigate the effects of ecologically relevant oral exposure to MSMA, including tissue distribution, growth parameters, and general health, including survival and immune function, of a model passerine, the zebra finch (Taeniopygia guttata). Nestling finches were orally dosed for 20 d from hatching to fledging with 4, 8, 12, 24, 36, or 72 mu g/g bw/d of monomethylarsonic acid (MMA(V), which corresponds to MSMA at physiological pH). Preliminary trials showed complete mortality at 36 and 72 mu g/g bw/d, and repeat trials also resulted in high mortality at 24 mu g/g bw/d. Surviving nestlings showed dose-dependent trends in accumulation of arsenic in blood and specific tissues, and decreased tarsi and wing cord length upon fledging. There were no observed effects of dosing on measured immune function (phytohemagglutinin [PHA], hematocrit, and leukocrit). The data obtained suggest that passerine nestlings may be at risk of mortality and reduced growth due to exposure to MSMA under current environmental conditions.},
	isbn = {1528-7394},
	url = {<Go to ISI>://000253154000001},
	author = {Albert, C. and Williams, T. D. and Morrissey, C. A. and Lai, V. W. M. and Cullen, W. R. and Elliott, J. E.}
}
