@article {682,
	title = {H/D exchange of gas phase bradykinin ions in a linear quadrupole ion trap},
	journal = {Journal of the American Society for Mass Spectrometry},
	volume = {14},
	number = {2},
	year = {2003},
	note = {ISI Document Delivery No.: 643ZYTimes Cited: 14Cited Reference Count: 51},
	month = {Feb},
	pages = {85-94},
	type = {Article},
	abstract = {The gas phase H/D exchange reaction of bradykinin ions, as well as fragment ions of bradykinin generated through collisions in an orifice skimmer region, have been studied with a linear quadrupole ion trap (LIT) reflectron time-of-flight (rTOF) mass spectrometer system. The reaction in the trap takes only tens of seconds at a pressure of few mTorr of D2O or CD3OD. The exchange rate and hydrogen exchange level are not sensitive to the trapping q value over a broad range, provided q is not close to the stability boundary (q = 0.908). The relative rates and hydrogen exchange levels of protonated and sodiated +1 and +2 ions are similar to those observed previously by others with a Fourier transform ion cyclotron resonance (FTICR) mass spectrometer system. The doubly and triply protonated ions show multimodal isotopic distributions, suggesting the presence of several different conformations. The y fragment ions show greater exchange rates and levels than a or b ions, and when water or ammonia is lost from the fragment ions, no exchange is observed. (J Am Soc Mass Spectrom 2003, 14, 85-94) (C) 2003 American Society for Mass Spectrometry.},
	keywords = {ACTIVATED DISSOCIATION, COLLISIONAL ACTIVATION, CYTOCHROME-C, HYDROGEN-DEUTERIUM EXCHANGE, HYDROGEN/DEUTERIUM EXCHANGE, INFRARED, IONIZATION MASS-SPECTROMETRY, OF-FLIGHT SYSTEM, PEPTIDE IONS, PROTEIN IONS, RADIATIVE DISSOCIATION},
	isbn = {1044-0305},
	url = {<Go to ISI>://000180894500001},
	author = {Mao, D. M. and Douglas, D. J.}
}
