@article {558,
	title = {An NMR approach to structural proteomics},
	journal = {Proceedings of the National Academy of Sciences of the United States of America},
	volume = {99},
	number = {4},
	year = {2002},
	note = {ISI Document Delivery No.: 524UKTimes Cited: 109Cited Reference Count: 28},
	month = {Feb},
	pages = {1825-1830},
	type = {Article},
	abstract = {The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMIR. Although there was variability among proteomes, overall 20\% of these proteins were found to be readily amenable to NMR structure determination. NMIR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.},
	keywords = {ASSIGNMENTS, CATH, DOMAIN, PROGRAM, PROTEINS, SPECTRA},
	isbn = {0027-8424},
	url = {<Go to ISI>://000174031100016},
	author = {Yee, A. and Chang, X. Q. and Pineda-Lucena, A. and Wu, B. and Semesi, A. and Le, B. and Ramelot, T. and Lee, G. M. and Bhattacharyya, S. and Gutierrez, P. and Denisov, A. and Lee, C. H. and Cort, J. R. and Kozlov, G. and Liao, J. and Finak, G. and Chen, L. and Wishart, D. and Lee, W. and McIntosh, L. P. and Gehring, K. and Kennedy, M. A. and Edwards, A. M. and Arrowsmith, C. H.}
}
