@article {11431,
	title = {Highly enantioselective, catalytic conjugate addition of cyanide to alpha,beta-unsaturated imides.},
	journal = {Journal of the American Chemical Society},
	volume = {125},
	year = {2003},
	month = {2003 Apr 16},
	pages = {4442-3},
	abstract = {(Salen)Al-Cl complex 1a catalyzes the asymmetric conjugate addition of hydrogen cyanide to alpha,beta-unsaturated imides in high yields and enantioselectivities. The cyanide adducts can readily be converted into a variety of useful chiral building blocks, including alpha-substituted-beta-amino acids and beta-substituted-gamma-aminobutyric acids. Mechanistic data obtained thus far point to a cooperative bimetallic mechanism for nucleophile and electrophile activation.},
	keywords = {ALKENES, amino acids, CATALYSIS, CYANIDES, gamma-Aminobutyric Acid, Imides, Stereoisomerism},
	issn = {0002-7863},
	author = {Sammis, G. M. and Jacobsen, Eric N.}
}
