@article {2495,
	title = {Broadening the Scope of Group 4 Hydroamination Catalysis Using a Tethered Ureate Ligand},
	journal = {Journal of the American Chemical Society},
	volume = {131},
	number = {51},
	year = {2009},
	note = {ISI Document Delivery No.: 543YATimes Cited: 12Cited Reference Count: 34Leitch, David C. Payne, Philippa R. Dunbar, Christine R. Schafer, Laurel L.},
	month = {Dec},
	pages = {18246-+},
	type = {Article},
	abstract = {A broadly applicable group-4-based precatalyst for the hydroamination of primary and secondary amines was developed. Screening experiments involving a series of amide and urea proligands led to the discovery of a tethered bis(ureate) zirconium complex with unprecedented reactivity in the intermolecular hydroamination of alkynes and the intramolecular hydroamination of alkenes. This catalyst system is effective with primary and secondary amines, 1,2-disubstituted alkenes, and heteroatom-containing functional groups, including ethers, silanes, amines, and heteroaromatics. The gem-disubstituent effect is not required for cyclization. The catalyst is generally regioselective for the anti-Markovnikov product of intermolecular alkyne hydroamination, and chemoselective for hydroamination over alpha-alkylation when forming 6- and 7-membered rings from aminoalkenes.},
	keywords = {ALKYNES, AMIDATE COMPLEXES, AMINES, AMINOALKENES, BOND FORMATION, INTRAMOLECULAR HYDROAMINATION, METAL-CATALYSTS, TITANIUM, UNACTIVATED ALKENES, ZIRCONIUM},
	isbn = {0002-7863},
	url = {<Go to ISI>://000273615800028},
	author = {Leitch, D. C. and Payne, P. R. and Dunbar, C. R. and Schafer, L. L.}
}
