@article {YANG202060,
	title = {A hydrophilic two-dimensional titanium-based metal-organic framework nanosheets for specific enrichment of glycopeptides},
	journal = {Analytica Chimica Acta},
	volume = {1119},
	year = {2020},
	pages = {60 - 67},
	abstract = {<p>A hydrophilic two-dimensional titanium-based metal-organic framework (MOF) nanosheets were prepared and applied to improve the glycopeptides enrichment efficiency. Seventeen N-linked glycopeptides from horseradish peroxidase (HRP) tryptic digests were readily identified and the results showed highly improved signal intensities. As the molar ratio of the mixture of tryptic digests of HRP, glycoprotein (HRP), and nonglycoprotein (BSA) reached 1:800:800, good selectivity of the Ti-MOF nanosheets were still clearly observed. As to human serum samples, 41 glycoproteins and 66 glycopeptides corresponding to 68\&nbsp;N-glycosylation sites were finally detected, which showed the good ability of the nanosheets material to enrich N-linked glycopeptides from complex human serum samples. Moreover, the Ti-MOF nanosheets exhibited unique stability and reusability even after being regenerated and reused for five times. It also performed a high sensitivity (1\&nbsp;\&times;\&nbsp;10\&minus;10\&nbsp;M HRP), a good enrichment capacity (250\&nbsp;mg/g) for glycopeptides enrichment and a high enrichment recovery of 78\%, suggesting a great application prospect for the enrichment of N-linked glycopeptides and the analysis glycoproteomic research.</p>},
	keywords = {Enrichment, Glycopeptides, MASS SPECTROMETRY, Metal-organic frameworks, Nanosheets},
	issn = {0003-2670},
	doi = {https://doi.org/10.1016/j.aca.2020.04.056},
	url = {http://www.sciencedirect.com/science/article/pii/S0003267020304839},
	author = {Shi-Shu Yang and Chen Wang and Xizhong Yu and Wenbin Shang and D. D. Y. Chen and Zhi-Yuan Gu}
}
@article {WANG20198,
	title = {Solvent-free high-throughput analysis of herbicides in environmental water},
	journal = {Analytica Chimica Acta},
	volume = {1071},
	year = {2019},
	month = {04/2019},
	pages = {8 - 16},
	abstract = {<p>A high throughput, and eco-friendly method based on solid-phase microextraction (SPME) combined with direct analysis in real time mass spectrometry (DART-MS) was established for the determination of trace pollutants in water. A laboratory-made SPME device coated with a metal organic framework (MIL-100 (M)) was fabricated for the on-site enrichment of triazine herbicides in environmental water, and the device was directly subjected to DART ionization (\&lt;20 s) for high resolution MS. The interactions between the target analytes and sorbents were investigated to improve the SPME device targeting specific pollutants, as well as to improve the desorption and ionization processes with DART-MS. Other factors were also systematically studied to obtain the optimal conditions, including pH, salinity, extraction temperature, pressure at the Vapur\&reg; interface, linear rail moving speed, gas temperature, extraction time, and sample volume. The limit of detection of target compounds were 5.0\&ndash;50.0 ng L\&minus;1 and the recoveries ranged from of 92.4\%\&ndash;125.7\%.</p>},
	keywords = {direct analysis in real time mass spectrometry, Metal-organic frameworks, SOLID-PHASE MICROEXTRACTION, Sustainable analytical method, Triazine herbicides},
	issn = {0003-2670},
	doi = {https://doi.org/10.1016/j.aca.2019.04.024},
	url = {http://www.sciencedirect.com/science/article/pii/S0003267019304453},
	author = {Jiaqin Wang and Qi Du and Xinrui You and Youqi Lv and Wentao Bi and Hongli Li and David D. Y. Chen}
}
