@article {2180,
	title = {Twenty years of interface development for capillary electrophoresis-electrospray ionization-mass spectrometry},
	journal = {Analytica Chimica Acta},
	volume = {627},
	number = {1},
	year = {2008},
	note = {ISI Document Delivery No.: 358IYTimes Cited: 22Cited Reference Count: 76Maxwell, E. Jane Chen, David D. Y.Sp. Iss. SI},
	month = {Oct},
	pages = {25-33},
	type = {Review},
	abstract = {Capillary electrophoresis-electrospray ionization-mass spectrometry has the potential to become a preferred tool for the analysis of biological mixtures and other complex samples. The development of improved interfaces in the past twenty years has been critical in demonstrating the feasibility of this technique. However, a compromise still exists between interfaces that give optimal performance and those that are practical for commercial applications. The first section of this review focuses on the technological advances in CE-ESI-MS as they relate to the key interface features for both sheath-flow and sheathless systems: delivery of the sheath liquid, shaping of the emitter tip, formation of electrical contact, and practicality in terms of ease of use and lifetime. In the second section, we review the fundamental processes that affect interface performance. Because of the complex natures of both capillary electrophoresis and electrospray ionization, flow rate, arrangement of the electrical circuit, electrochemistry, tip geometry and location of electrical contact must all be carefully managed in the design of a successful interface. (C) 2008 Elsevier B.V. All rights reserved.},
	keywords = {BEVELED EDGE, capillary electrophoresis, DESIGN, electrospray ionization, EMITTERS, FLOW NANOSPRAY, FUSED-SILICA CAPILLARY, interface development, JUNCTION INTERFACE, LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY, MASS SPECTROMETRY, MICRO-ELECTROSPRAY, SHEATHLESS CAPILLARY, ZONE-ELECTROPHORESIS},
	isbn = {0003-2670},
	url = {<Go to ISI>://000259911600003},
	author = {Maxwell, E. J. and Chen, D. D. Y.}
}
@article {497,
	title = {Multiple sprayer system for high-throughput electrospray ionization mass spectrometry},
	journal = {Rapid Communications in Mass Spectrometry},
	volume = {16},
	number = {20},
	year = {2002},
	note = {ISI Document Delivery No.: 604ADTimes Cited: 13Cited Reference Count: 32},
	pages = {1982-1990},
	type = {Article},
	abstract = {<p>A multiple sprayer electrospray ion source for high-throughput analysis is described. The ion source is comprised of multiple electrospray capillaries, each with an ion lens located near the tip. The electric potentials applied to the ion lenses are used to control the sprayers. The use of ion lenses eliminates the need for mechanical blocking devices to selectively enable or disable the sprayers, and results in a less expensive and more reliable set-up. Sprayers can be enabled or disabled within approximately 50-250 ms when the lens potentials are controlled manually. For simultaneous operation of multiple electrospray capillaries, it is advantageous to orient the capillaries so that the spray from each passes directly in front of the entrance aperture of the mass spectrometer. Copyright (C) 2002 John Wiley Sons, Ltd.</p>},
	keywords = {ARRAYS, capillary electrophoresis, INTERFACE, LIBRARIES, LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY, SEPARATE SAMPLE},
	isbn = {0951-4198},
	doi = {10.1002/rcm.806},
	url = {https://onlinelibrary.wiley.com/doi/full/10.1002/rcm.806},
	author = {Schneider, B. B. and Douglas, D. J. and Chen, D. D. Y.}
}
