@article {341,
	title = {Accurately describing weak analyte-additive interactions by capillary electrophoresis},
	journal = {Electrophoresis},
	volume = {23},
	number = {6},
	year = {2002},
	note = {ISI Document Delivery No.: 536KNTimes Cited: 12Cited Reference Count: 33},
	month = {Mar},
	pages = {880-888},
	type = {Article},
	abstract = {When modeling analyte-additive interactions in capillary electrophoresis (CE), it is necessary to correct for all changes in the apparent electrophoretic mobility of an analyte that are not due to specific binding. Current models based on dynamic complexation have corrected for bulk viscosity changes in the background electrolyte (BGE) when additives are used, while assuming negligible changes in the dielectric constant and other physicochemical properties of the solution. In this report, a study of weak interactions between deoxyribonucleotides and hydroxypropyl-beta-cyclodextrin (HP-beta-CD) revealed significant nonideality in binding isotherms. Changes in the dielectric properties of the solution due to the addition of high concentrations of HP-beta-CD to the BGE was observed to alter the electrophoretic mobility of analytes. A relative dielectric correction factor was required to normalize analyte mobilities to a reference state of zero additive concentration. The use of both a relative dielectric factor and a viscosity correction factor was found to increase the accuracy of the model, reflected by a higher degree of correlation between predicted and measured analyte mobilities. This type of correction is particularly relevant when studying weak analyte binding interactions or when using high concentrations of additive in the BGE. This work is vital for accurate determination of weak binding constants and mobility values, as well as providing a deeper understanding of the fundamental parameters influencing a separation in CE.},
	keywords = {analyte-additive interactions, BETA-CYCLODEXTRIN, binding isotherms, capillary electrophoresis, CHIRAL SEPARATION, cyclodextrin, deoxyribonucleotides, DYNAMIC COMPLEXATION, ELECTROKINETIC CHROMATOGRAPHY, ELECTROPHORESIS, ENANTIOMERS, MIGRATION BEHAVIOR, MODEL, OPTIMIZATION, QUANTITATIVE DESCRIPTION, viscosity-dielectric corrections factors, weak, ZONE},
	isbn = {0173-0835},
	url = {<Go to ISI>://000174699400008},
	author = {Britz-McKibbin, P. and Chen, D. D. Y.}
}
@article {4738,
	title = {Velocity-difference induced focusing of nucleotides in capillary electrophoresis with a dynamic pH junction},
	journal = {Analytical Chemistry},
	volume = {72},
	number = {8},
	year = {2000},
	note = {ISI Document Delivery No.: 304RDTimes Cited: 122Cited Reference Count: 35},
	month = {Apr},
	pages = {1729-1735},
	type = {Article},
	abstract = {Velocity-difference induced focusing (V-DIF) of nucleotides was achieved by using a dynamic pH junction in capillary electrophoresis (CE) with UV detection. The influence of specific analyte properties, such as nucleotide base structure, sugar structure, and degree of phosphorylation, is examined. The pK(a) values and berate complexation with vicinal diols are important factors that caused the focusing. Therefore, the pH and berate content in the sample and background electrolyte can be adjusted to optimize the focusing effect. This method allows the injection of large volumes of sample (similar to 300 nL), resulting in at least 50-fold improvement in concentration sensitivity. The detection limit of 4.0 x 10(-8) M for nucleotides can be achieved in favorable conditions. V-DIF can be also applied to nucleotide pool analysis from cell extracts to improve the concentration sensitivity of CE and to reduce the time-consuming steps of desalting and off-line preconcentration that are often required for assays of nucleotides from biological samples.},
	keywords = {DNA-ADDUCTS, ELECTROPHORESIS, INJECTION, ISOTACHOPHORESIS, MICELLAR ELECTROKINETIC CHROMATOGRAPHY, NEUTRAL ANALYTES, SAMPLE SELF-STACKING, SEPARATION, TRIPHOSPHATES, VOLUME, ZONE},
	isbn = {0003-2700},
	url = {<Go to ISI>://000086497200001},
	author = {Britz-McKibbin, P. and Bebault, G. M. and Chen, D. D. Y.}
}
@article {4528,
	title = {Elemental analysis with quadrupole mass filters operated in higher stability regions},
	journal = {Journal of Analytical Atomic Spectrometry},
	volume = {14},
	number = {8},
	year = {1999},
	note = {ISI Document Delivery No.: 229LPTimes Cited: 23Cited Reference Count: 47},
	month = {Aug},
	pages = {1111-1119},
	type = {Article},
	abstract = {Operation of quadrupole mass filters in higher zones of stability is described with an emphasis on the potential for elemental mass spectrometry. The higher zones allow a resolution at half height of up to 9000 on atomic ions and make possible unit resolution on ions with kinetic energies up to several thousand electron volts. The theory of quadrupole operation is briefly reviewed. Operation of quadrupoles in the third stability region with Mathieu parameters (a,q)approximate to(3,3) and the second stability region with (a,q)approximate to(0.02, 7.55) is described in detail. Previously unpublished data showing the variation of resolution with ion energy are presented. The variation of transmission with resolution is compared with previous calculations and with new calculations presented here.},
	keywords = {2ND, ANALYZER, ATMOSPHERE, DIAGRAM, HELIUM, HIGH-RESOLUTION, ICP-MS, SEPARATION MODE, SPECTROMETER, ZONE},
	isbn = {0267-9477},
	url = {<Go to ISI>://000082196300002},
	author = {Du, Z. H. and Douglas, D. J. and Konenkov, N.}
}
@article {3861,
	title = {High resolution inductively coupled plasma mass spectra with a quadrupole mass filter},
	journal = {Rapid Communications in Mass Spectrometry},
	volume = {10},
	number = {6},
	year = {1996},
	note = {ISI Document Delivery No.: UJ502Times Cited: 26Cited Reference Count: 30},
	pages = {649-652},
	type = {Article},
	abstract = {{An inductively coupled plasma mass spectrometer (ICP-MS) system is described in which the quadrupole mass filter can be operated conventionally or in the {\textquoteright}second{\textquoteright} stability region (with Mathieu parameters q=7.547},
	keywords = {2ND STABILITY REGION, DIAGRAM, SEPARATION, SPECTROMETRY, ZONE},
	isbn = {0951-4198},
	url = {<Go to ISI>://A1996UJ50200008},
	author = {Ying, J. F. and Douglas, D. J.}
}
