@article {2415,
	title = {X-ray Crystal Analysis of a TASP: Structural Insights of a Cavitein Dimer},
	journal = {Journal of the American Chemical Society},
	volume = {131},
	number = {21},
	year = {2009},
	note = {ISI Document Delivery No.: 451QOTimes Cited: 0Cited Reference Count: 75Freeman, Jon O. Lee, Woo Cheol Murphy, Michael E. P. Sherman, John C.},
	month = {Jun},
	pages = {7421-7429},
	type = {Article},
	abstract = {Cavitein Q4 is a template assembled synthetic protein designed for X-ray crystallographic analysis. It is based on a previous monomeric helical bundle cavitein (N1GG) that consists of four identical parallel helical peptides. Crystals that were grown in the presence of bromide ions were used to solve the initial phases via single-wavelength anomalous dispersion (SAD). A 1.4 angstrom resolution data set was then refined starting with the SAD phases to provide the crystal structure of cavitein Q4. The crystal structure revealed cavitein Q4 as an asymmetric dimer, although the cavitein appears to be largely monomeric in solution. A comparative analysis is carried out to discern any intrinsic differences between Q4 and its parent cavitein N1GG. We present herein the first X-ray crystal structure of a TASP system and relate this structure to the solution data for both Q4 and its parent N1GG.},
	keywords = {4-HELIX BUNDLE, ALPHA-HELICES, ANALYTICAL, ANION-BINDING, ASSEMBLED SYNTHETIC PROTEINS, DE-NOVO PROTEINS, NATIVE-LIKE STRUCTURE, PEPTIDE-CAVITANDS, PROTEINS, SELF-ASSOCIATION, ULTRACENTRIFUGATION, UPPER RIM},
	isbn = {0002-7863},
	url = {<Go to ISI>://000266484900042},
	author = {Freeman, J. O. and Lee, W. C. and Murphy, M. E. P. and Sherman, J. C.}
}
@article {3908,
	title = {Redefining the separation factor: A potential pathway to a unified separation science},
	journal = {Electrophoresis},
	volume = {18},
	number = {15},
	year = {1997},
	note = {ISI Document Delivery No.: YW557Times Cited: 20Cited Reference Count: 38},
	month = {Dec},
	pages = {2928-2934},
	type = {Article},
	abstract = {Understanding the separation process in capillary electrophoresis (CE leads to the unification of the theories for separation science; While the separation of analytes is governed by equilibria in chromatography, and by (centrifugal) field in ultracentrifugation, the separation in CE is governed by both equilibria and (electric) field. Therefore, a comprehensive separation theory that describes the separation process of analytes in CE should be able to describe the separation processes in both chromatography and ultracentrifugation. In this paper, we propose that individual capacity factors for each analyte species be used to describe the migration behavior of an analyte. The effect of field on each analyte species, as well as the effect of equilibria are considered in deriving a generalized equation that is applicable for all separation techniques. The separation factor defined at present does not directly relate to the migration rates of the analytes, and therefore can not be used in a generalized theory. We propose that the ratio of the migration rates of a pair of analytes (gamma) should be used as the separation factor, instead of the ratio of the two capacity factors. When gamma is used to describe the separation of two closely migrating analytes, all separation techniques have the same resolution equation.},
	keywords = {BETA-CYCLODEXTRIN, capacity factor, capillary electrophoresis, CHROMATOGRAPHY, ELECTROKINETIC CHROMATOGRAPHY, ELECTROPHORETIC CHIRAL SEPARATIONS, ENANTIOMERS, LIQUID-CHROMATOGRAPHY, PARAMETERS, RESOLUTION, SELECTIVITY, separation factor, TIOCONAZOLE, ULTRACENTRIFUGATION, ZONE ELECTROPHORESIS},
	isbn = {0173-0835},
	url = {<Go to ISI>://000071948300033},
	author = {Bowser, M. T. and Bebault, G. M. and Peng, X. J. and Chen, D. D. Y.}
}
