@article {2682,
	title = {Construction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations},
	journal = {Chemical Communications},
	number = {38},
	year = {2009},
	note = {ISI Document Delivery No.: 498CXTimes Cited: 3Cited Reference Count: 41Zhai, Huimin Zlotorzynska, Maria Sammis, Glenn},
	pages = {5716-5718},
	type = {Article},
	abstract = {Nitrogen-centered radical cyclizations onto silyl enol ethers were utilized for the syntheses of protected polyhydroxylated pyrrolidines 2-hydroxymethyl-3-hydroxypyrrolidine and 1,4-dideoxy-1,4-imino-L-ribitol.},
	keywords = {1, 4-DIDEOXY-1, 4-IMINO-L-RIBITOL, ADDITIONS, AMINYL RADICALS, GENERATION, glycosidase, inhibitors, NATURAL OCCURRENCE, ring expansion, ROUTE, STRAIGHTFORWARD SYNTHESIS, THERAPEUTIC APPLICATIONS},
	isbn = {1359-7345},
	url = {<Go to ISI>://000270115300013},
	author = {Zhai, H. M. and Zlotorzynska, M. and Sammis, G.}
}
@article {1109,
	title = {An asymmetric formal synthesis of fasicularin},
	journal = {Chemistry-a European Journal},
	volume = {11},
	number = {2},
	year = {2005},
	note = {ISI Document Delivery No.: 887VLTimes Cited: 20Cited Reference Count: 138},
	month = {Jan},
	pages = {639-649},
	type = {Review},
	abstract = {An asymmetric formal synthesis of fasicularin (1) is described. This natural product, isolated from the extracts of the marine invertebrate Nephteis fasicularis, has shown modest cytotoxicity towards Vero cells. Fasicularin is among only two members of the cylindricine family of natural products, along with lepadiformine (2), to possess a trans A-B ring junction. Key steps of this approach to 1 involve a siloxy-epoxide semipinacol rearrangement of 5 to 6, a B-alkyl Suzuki-Miyaura coupling reaction by using enol trifluoromethanesulfonate 19 and a substrate-directed hydrogenation reaction of 24. This formal synthesis also highlights the difficulty in the incorporation of the thiocyanate functionality present in 1.},
	keywords = {ALKALOIDS, ALPHA-HYDROXY EPOXIDES, ASCIDIAN CLAVELINA-CYLINDRICA, BETA-SILOXY ALDEHYDES, CROSS-COUPLING, CROSS-COUPLING REACTION, DIELS-ALDER REACTION, ENANTIOSPECIFIC, EPOXY SILYL ETHERS, MARINE ALKALOID LEPADIFORMINE, REGIOSELECTIVE OLEFIN INSERTION, ring expansion, SEMI-PINACOL REARRANGEMENT, semipinacol rearrangement, spirocycle},
	isbn = {0947-6539},
	url = {<Go to ISI>://000226333500017},
	author = {Fenster, M. D. B. and Dake, G. R.}
}
@article {639,
	title = {N-bromosuccinimide promoted ring expansion reactions: Diastereoselective formation of functionalized azaspirocyclic cyclopentanones},
	journal = {Synlett},
	number = {14},
	year = {2003},
	note = {ISI Document Delivery No.: 741GTTimes Cited: 10Cited Reference Count: 30},
	month = {Nov},
	pages = {2131-2134},
	type = {Article},
	abstract = {N-Bromosuccinimide (NBS) induces ring enlargements of 2-(1-hydroxycyclobutyl)-p-toluenesulfonylenamides such as 1. These high yielding reactions typically occur with good diastereoselectivity. This ring expansion protocol under neutral conditions forms compounds that are potentially versatile intermediates for the construction of spirocycle-containing alkaloids.},
	keywords = {bromine, CONSTRUCTION, entry, HALICHLORINE, ION, KETONES, PINNAIC ACID, piperidines, REDUCTION, ring expansion, spiro compounds, SPIROCYCLIC CORE, STEREOSELECTIVE},
	isbn = {0936-5214},
	url = {<Go to ISI>://000186450900005},
	author = {Hurley, P. B. and Dake, G. R.}
}
