@article {2622,
	title = {Bis- and Mono(amidate) Complexes of Yttrium: Synthesis, Characterization, and Use as Precatalysts for the Hydroamination of Aminoalkenes},
	journal = {Organometallics},
	volume = {28},
	number = {14},
	year = {2009},
	note = {ISI Document Delivery No.: 473AWTimes Cited: 11Cited Reference Count: 47Stanlake, Louisa J. E. Schafer, Laurel L.},
	month = {Jul},
	pages = {3990-3998},
	type = {Article},
	abstract = {A high-yielding synthetic route is disclosed for yttrium bis- and mono(amidate) complexes using the reaction of amide proligand and Y(N(SiMe3)(2))(3) starting materials. The structure, bonding, and solution phase characterization data for this new class of complexes are presented. The modular nature of the amidate ligand allows for easy addition of electron-withdrawing CF3 groups in the ligand backbone to tune electronic properties of the resulting precatalysts. The amidate ligands in the bis(amidate) complexes were found to be highly fluxional on the NMR time scale, while the mono(amidate) yttrium complex required heating to 110 degrees C before ligand redistribution was observed. Three bis(amidate) complexes with differing electronic properties and one mono(amidate) complex have been used as precatalysts for hydroamination using a wide range of aminoalkene substrates. Bis(amidate) complexes bearing the more electron-withdrawing amidate ligands were found to be the most active precatalysts for intramolecular alkene hydroamination.},
	keywords = {ALKENES, AMIDATE COMPLEXES, ASYMMETRIC HYDROAMINATION, EARTH, GROUP-3, HYDROAMINATION, INTRAMOLECULAR, LANTHANIDE, LIGANDS, metals, OLEFINS, ORGANOLANTHANIDE-CATALYZED HYDROAMINATION},
	isbn = {0276-7333},
	url = {<Go to ISI>://000268176700006},
	author = {Stanlake, L. J. E. and Schafer, L. L.}
}
@article {1601,
	title = {A pentagonal pyramidal zirconium imido complex for catalytic hydroamination of unactivated alkenes},
	journal = {Organometallics},
	volume = {25},
	number = {17},
	year = {2006},
	note = {ISI Document Delivery No.: 070PZTimes Cited: 66Cited Reference Count: 40Thomson, Robert K. Bexrud, Jason A. Schafer, Laurel L.},
	month = {Aug},
	pages = {4069-4071},
	type = {Article},
	abstract = {The first, isolable group 4 imido complexes capable of promoting intramolecular olefin hydroamination for the preparation of N-containing heterocycles are presented. The structurally characterized 6-coordinate bis(amidate)-supported zirconium imido complex is a rare example of distorted-pentagonal-pyramidal geometry.},
	keywords = {ALKYNE HYDROAMINATION, allenes, AMIDATE COMPLEXES, BIS(AMIDATE) TITANIUM PRECATALYST, C-H ACTIVATION, HYDROAMINATION, INTERMOLECULAR HYDROAMINATION, INTRAMOLECULAR, REACTIVITY, TEMPERATURE, TI(NME2)(4)},
	isbn = {0276-7333},
	url = {<Go to ISI>://000239536800007},
	author = {Thomson, R. K. and Bexrud, J. A. and Schafer, L. L.}
}
@article {3819,
	title = {Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1},
	journal = {Protein Science},
	volume = {5},
	number = {2},
	year = {1996},
	note = {ISI Document Delivery No.: TU724Times Cited: 46Cited Reference Count: 66},
	month = {Feb},
	pages = {296-309},
	type = {Article},
	abstract = {Several members of the ets gene family of transcription factors show negative regulation of DNA binding by intramolecular interactions. A structural mechanism for this auto-inhibition is investigated using a 161-residue N-terminal deletion mutant of murine Ets-1, Ets-1 Delta N280. This protein shows a similar reduced affinity for DNA as native Ets-1 because it contains the ETS domain in context of the flanking amino- and carboxy-terminal regions that together mediate repression of DNA binding. The secondary structure of Ets-1 Delta N280 was determined using NMR chemical shift, NOE, J coupling, and amide hydrogen exchange information. In addition to the winged helix-turn-helix ETS domain, Ets-1 Delta N280 contains two alpha-helices in the amino-terminal inhibitory region and one alpha-helix in the carboxy-terminal inhibitory region. Chemical shift comparisons were made between this protein and an activated form of Ets-1 lacking the amino-terminal inhibitory region. The spectral differences demonstrate that the amino- and carboxy-terminal inhibitory sequences are structurally coupled to one another, thus explaining the observation that both regions are required for the repression of DNA binding. Furthermore, these data show that the inhibitory sequences also interact directly with the first helix of the intervening ETS domain, thereby providing a pathway for the repression of DNA binding. These results lead to a model of an inhibitory module in Ets-1 composed of both the amino- and carboxy-terminal regions interfaced with the ETS domain. This establishes the structural framework for understanding the intramolecular inhibition of Ets-1 DNA binding.},
	keywords = {3-DIMENSIONAL NMR-SPECTROSCOPY, allosteric, ASSIGNMENT, CRYSTAL-STRUCTURE, DNA binding, DNA-BINDING MOTIF, ETS domain, Ets-1 and Ets-2, FACTORS, H-1, INHIBITION, INTRAMOLECULAR, LARGER PROTEINS, N-15 NMR, NMR, protein structure, SPECTRA, transcription, V-ETS, winged helix-turn-helix},
	isbn = {0961-8368},
	url = {<Go to ISI>://A1996TU72400014},
	author = {Skalicky, J. J. and Donaldson, L. W. and Petersen, J. M. and Graves, B. J. and McIntosh, L. P.}
}
