@article {doi:10.1002/anie.201708529,
	title = {Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes},
	journal = {Angewandte Chemie International Edition},
	volume = {56},
	number = {49},
	year = {Submitted},
	pages = {15603-15606},
	abstract = {Abstract A family of environment-sensitive shape-shifting molecules have been developed as flexible fluorescent (FlexFluor) dyes for biological imaging applications. These compounds feature a flexible bithiophene-based fluorophore that gives rise to different emission colors in lipophilic or hydrophilic environments, as well as side groups that can be synthetically modified with ease. FlexFluor dyes are the first fluorescent dyes in which emission color can be used to indicate lipid/water environments. The behavior of these dyes in different solvents was studied, and used to simultaneously highlight lipid and water contents in adipose and brain tissues using optical fluorescence microscopy.},
	keywords = {ADIPOCYTES, bichromatic dyes, lipophilicity, myelin sheath, NEURONS},
	doi = {10.1002/anie.201708529},
	url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201708529},
	author = {Cao Yang and Wang Xiaozhu and Shi Xiaolei and Clee Susanne M. and McGeer Patrick L. and Wolf Michael O. and Orvig Chris}
}
@article {ANIE:ANIE201708529,
	title = {Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent Dyes},
	journal = {Angew. Chem. Int. Ed.},
	volume = {56},
	number = {49},
	year = {2017},
	pages = {15603{\textendash}15606},
	keywords = {ADIPOCYTES, bichromatic dyes, lipophilicity, myelin sheath, NEURONS},
	issn = {1521-3773},
	doi = {10.1002/anie.201708529},
	url = {http://dx.doi.org/10.1002/anie.201708529},
	author = {Cao, Yang and Wang, Xiaozhu and Shi, Xiaolei and Clee, Susanne M. and McGeer, Patrick L. and Wolf, Michael O. and Orvig, Chris}
}
@article {2775,
	title = {THE SYNTHESIS AND X-RAY STRUCTURES OF THE GEOMETRIC ISOMERS OF 1-AMINO-1,2-CYCLOPENTANEDICARBOXYLIC ACID},
	journal = {Canadian Journal of Chemistry-Revue Canadienne De Chimie},
	volume = {71},
	number = {1},
	year = {1993},
	note = {ISI Document Delivery No.: KN060Times Cited: 5Cited Reference Count: 9},
	month = {Jan},
	pages = {76-83},
	type = {Article},
	abstract = {The geometric isomers of 1-amino-1,2-cyclopentanedicarboxylic acid were isolated as the hydrolysis products of 2-cyclopentanecarboxylic acid-5,5{\textquoteright}-hydantoin. The hydantoin ester was formed from ethyl -2-oxocyclopentanecarboxylate via a Bucherer-Bergs reaction. Hydrolysis of the hydantoin at elevated temperatures gave a mixture of trans- and cis-1-amino-1,2-cyclopentanedicarboxylic acids indicating epimerization during hydrolysis. The trans product has not been described previously and the cis not extensively characterized. X-ray crystallography reveals that both isomers are zwitterionic in the solid state and the cis isomer molecules are linked by unusually strong hydrogen bonding. Structures were confirmed by C-13 NMR, X-ray crystallography, and elemental analysis. Physical data are also presented.},
	keywords = {BUCHERER-BERGS, NEURONS, STEREOCHEMISTRY, STRECKER REACTIONS},
	isbn = {0008-4042},
	url = {<Go to ISI>://A1993KN06000011},
	author = {Curry, K. and McLennan, H. and Rettig, S. J. and Trotter, J.}
}
