Pierre Kennepohl

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  1. Pierre Kennepohl
  2. Pierre Kennepohl

Pierre Kennepohl

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Featured Publications

He, W. ; Patrick, B. O. ; Kennepohl, P. Identifying The Missing Link In Catalyst Transfer Polymerization. Nature Commun. 2018, 9, 3866.
Mustoe, C. L. ; Gunabalasingam, M. ; Yu, D. ; Patrick, B. O. ; Kennepohl, P. Probing Covalency In Halogen Bonds Through Donor K-Edge X-Ray Absorption Spectroscopy: Polyhalides As Coordination Complexes. Faraday Discuss. 2017, 203, 79-91.
Parlane, F. G. L. ; Mustoe, C. L. ; Kellett, C. W. ; Simon, S. J. ; Swords, W. B. ; Meyer, G. J. ; Kennepohl, P. ; Berlinguette, C. P. Spectroscopic Detection Of Halogen Bonding Resolves Dye Regeneration In The Dye-Sensitized Solar Cell. Nature Commun. 2017, 8, 1761.
Desnoyer, A. N. ; Behyan, S. ; Patrick, B. O. ; Dauth, A. ; Love, J. A. ; Kennepohl, P. Reexamining Oxidation States During The Synthesis Of 2-Rhodaoxetanes From Olefins. Inorganic Chemistry 2016, 55, 13-15.
Robinson, S. W. ; Mustoe, C. L. ; White, N. G. ; Brown, A. ; Thompson, A. L. ; Kennepohl, P. ; Beer, P. D. Evidence For Halogen Bond Covalency In Acyclic And Interlocked Halogen-Bonding Receptor Anion Recognition. J. Am. Chem. Soc. 2015, 137, 499-507.

Research and Teaching Interests

 My research centres on probing the relationship between electronic structure and reactivity in catalytic systems. Emphasis is placed on the application of element-specific spectroscopic techniques such as X-ray Absorption Spectroscopy (XAS) and X-ray Emission Spectroscopy (XES) as a means of generating experimentally-validated electronic and geometric structure descriptions of catalytically relevant species.  

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Recent investigations by Thamy Sriskandakumar, in collaboration with Prof Peter J. Sadler and members of his group provided new insights into the possible mechanism of action of a series of potent cytotoxic ruthenium(II) arene complexes of interest as potential anticancer drugs. (see J. Am. Chem. Soc. 2009, 131(37), 13355–13361)

Other spectroscopic techniques (such as UV/Vis/NIR Absorption and EPR), as well as computational methods, are used as complementary methods to explore such species. We have varied interests in a number of areas spanning bioinorganic, organometallic, and physical inorganic chemistry. Specific projects are (as much as possible) tailored to the specific interests and strengths of students.

Contact

Real name: 
Pierre Kennepohl
Email: 

Curriculum Vitae

B.Sc., Concordia - Canada Scholar (Nick Serpone, 1993)

Ph.D., Stanford - NSERC Centennial Scholar (Edward I Solomon, 2002)

PDF, Caltech (Harry B Gray & Adrian Ponce, 2002-3)

Publications

2019

Desnoyer, A. N. ; He, W. ; Behyan, S. ; Chiu, W. ; Love, J. A. ; Kennepohl, P. The Importance Of Ligand-Induced Backdonation In The Stabilization Of Square Planar D(10) Nickel -Complexes. CHEMISTRY-A EUROPEAN JOURNAL 2019, 25, 5259-5268.
Zhang, W. ; Mo, J. Yi; He, W. ; Kennepohl, P. ; Sammis, G. M. Regiocontrolled And Stereoselective Syntheses Of Tetrahydrophthalazine Derivatives Using Radical Cyclizations. CHEMISTRY-A EUROPEAN JOURNAL 2019, 25, 976-980.
Transue, W. J. ; Nava, M. ; Terban, M. W. ; Yang, J. ; Greenberg, M. W. ; Wu, G. ; Foreman, E. S. ; Mustoe, C. L. ; Kennepohl, P. ; Owen, J. S. ; Billinge, S. J. L. ; Kulik, H. J. ; Cummins, C. C. Anthracene As A Launchpad For A Phosphinidene Sulfide And For Generation Of A Phosphorus-Sulfur Material Having The Composition P2S, A Vulcanized Red Phosphorus That Is Yellow. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2019, 141, 431-440.

2018

D. Beattie, D. ; Lascoumettes, G. ; Kennepohl, P. ; Love, J. A. ; Schafer, L. L. Disproportionation Reactions Of An Organometallic Ni(I) Amidate Complex: Scope And Mechanistic Investigations. Organometallics 2018, 37, 1392-1399.
He, W. ; Patrick, B. O. ; Kennepohl, P. Identifying The Missing Link In Catalyst Transfer Polymerization. Nature Commun. 2018, 9, 3866.
Xue, W. ; Kennepohl, P. ; Ruddick, J. N. R. Reacted Copper(Ii) Concentrations In Amine Amended Micronized Copper Treated Red Pine And Lodgepole Pine. Eur. J. Wood Prod. 2018, 76, 337-343.

2017

Aakeröy, C. B. ; Alavi, S. ; Brammer, L. ; Bryce, D. L. ; Clark, T. ; Del Bene, J. E. ; Edwards, A. J. ; Esterhuysen, C. ; Row, T. N. Guru; Kennepohl, P. ; Legon, A. C. ; Lloyd, G. O. ; Murray, J. S. ; Pennington, W. T. ; Politzer, P. ; Riley, K. E. ; Rosokha, S. V. ; Scheiner, S. ; Tsuzuki, S. ; Vargas-Baca, I. Computational Approaches And Sigma-Hole Interactions: General Discussion. Faraday Discuss. 2017, 203, 131-163.
Mustoe, C. L. ; Gunabalasingam, M. ; Yu, D. ; Patrick, B. O. ; Kennepohl, P. Probing Covalency In Halogen Bonds Through Donor K-Edge X-Ray Absorption Spectroscopy: Polyhalides As Coordination Complexes. Faraday Discuss. 2017, 203, 79-91.
Hobbs, M. G. ; Dufresne, P. ; Behyan, S. ; Kennepohl, P. Mechanisms Of Varnish Formation And Implications For The Use Of Varnish-Removal Technology. In 72nd Annual Meeting and Exhibition of the Society of Tribologists and Lubrication Engineers, STLE 2017; 72nd Annual Meeting and Exhibition of the Society of Tribologists and Lubrication Engineers, STLE 2017; 2017.
Aakeröy, C. B. ; Alavi, S. ; Beyeh, N. Kodiah; Brammer, L. ; Branca, M. ; Bryce, D. L. ; Christopherson, J. - C. ; Clark, T. ; Cottrell, S. J. ; Del Bene, J. E. ; Dichiarante, V. ; Edwards, A. J. ; Erdelyi, M. ; Esterhuysen, C. ; Fourmigué, M. ; Friščić, T. ; Kennepohl, P. ; Legon, A. C. ; Lloyd, G. O. ; Murray, J. S. ; Mustoe, C. L. ; Pennington, W. T. ; Rosokha, S. V. ; Choudhury, A. Roy; Scheiner, S. ; Szell, P. M. J. ; Taylor, M. S. ; Tsuzuki, S. Solid-State Chemistry And Applications: General Discussion. Faraday Discuss. 2017, 203, 459-483.
Parlane, F. G. L. ; Mustoe, C. L. ; Kellett, C. W. ; Simon, S. J. ; Swords, W. B. ; Meyer, G. J. ; Kennepohl, P. ; Berlinguette, C. P. Spectroscopic Detection Of Halogen Bonding Resolves Dye Regeneration In The Dye-Sensitized Solar Cell. Nature Commun. 2017, 8, 1761.
Aakeröy, C. B. ; Alavi, S. ; Beer, P. D. ; Beyeh, N. Kodiah; Brammer, L. ; Bryce, D. L. ; Clark, T. ; Cottrell, S. J. ; Del Bene, J. E. ; Edwards, A. J. ; Esterhuysen, C. ; Friščić, T. ; Row, T. N. Guru; Kennepohl, P. ; Lloyd, G. O. ; Choudhury, A. Roy; Scheiner, S. ; Southern, S. A. ; Taylor, M. S. ; Tsuzuki, S. ; Vargas-Baca, I. Beyond The Halogen Bond: General Discussion. Faraday Discuss. 2017, 203, 227-244.
Aakeröy, C. B. ; Beer, P. D. ; Beyeh, N. Kodiah; Brammer, L. ; Branca, M. ; Bryce, D. L. ; Del Bene, J. E. ; Edwards, A. J. ; Erdelyi, M. ; Esterhuysen, C. ; Fourmigué, M. ; Kennepohl, P. ; Lee, L. Myongwon; Mosquera, M. E. G. ; Murray, J. S. ; Mustoe, C. L. ; Pennington, W. T. ; Politzer, P. ; Riley, K. E. ; Rosokha, S. V. ; Scheiner, S. ; Taylor, M. S. ; Tsuzuki, S. ; Vargas-Baca, I. ; Xu, Y. The Halogen Bond In Solution: General Discussion. Faraday Discuss. 2017, 203, 347-370.

2016

Liang, N. ; Xue, W. ; Kennepohl, P. ; Kitts, D. D. Interactions Between Major Chlorogenic Acid Isomers And Chemical Changes In Coffee Brew That Affect Antioxidant Activities. Food Chem. 2016, 213, 251-259.
Desnoyer, A. N. ; Behyan, S. ; Patrick, B. O. ; Dauth, A. ; Love, J. A. ; Kennepohl, P. Reexamining Oxidation States During The Synthesis Of 2-Rhodaoxetanes From Olefins. Inorg. Chem. 2016, 55, 13-15.
Xue, W. ; Ruddick, J. N. R. ; Kennepohl, P. Solubilisation And Chemical Fixation Of Copper(Ii) In Micronized Copper Treated Wood. Dalton Trans. 2016, 45, 3679-3686.
Majhi, P. Kumar; Chow, K. C. F. ; Hsieh, T. H. H. ; Bowes, E. G. ; Schnakenburg, G. ; Kennepohl, P. ; Streubel, R. ; Gates, D. P. Even The Normal Is Abnormal: N-Heterocyclic Carbene C-2 Binding To A Phosphaalkene Without Breaking The P=C Pi-Bond. Chem.Commun. 2016, 52, 998-1001.

2015

Sriskandakumar, T. ; Behyan, S. ; Habtemariam, A. ; Sadler, P. J. ; Kennepohl, P. Electrophilic Activation Of Oxidized Sulfur Ligands And Implications For The Biological Activity Of Ruthenium(Ii) Arene Anticancer Complexes. Inorg. Chem. 2015, 54, 11574-11580.
Chong, E. ; Xue, W. ; Storr, T. ; Kennepohl, P. ; Schafer, L. L. Pyridonate-Supported Titanium(Iii). Benzylamine As An Easy-To-Use Reductant. Organometallics 2015, 34, 4941-4945.
Stirling, R. ; Ruddick, J. N. R. ; Xue, W. ; Morris, P. I. ; Kennepohl, P. Characterization Of Copper In Leachates From Acq- And Mcq-Treated Wood And Its Effects On Basidiospore Germination. Wood Fibre Chem. 2015, 47, 209-216.
Xue, W. ; Kennepohl, P. ; Ruddick, J. N. R. Reacted Copper(Ii) Concentrations In Earlywood And Latewood Of Micronized Copper-Treated Canadian Softwood Species. Holzforschung 2015, 69, 509-512.
Robinson, S. W. ; Mustoe, C. L. ; White, N. G. ; Brown, A. ; Thompson, A. L. ; Kennepohl, P. ; Beer, P. D. Evidence For Halogen Bond Covalency In Acyclic And Interlocked Halogen-Bonding Receptor Anion Recognition. J. Am. Chem. Soc. 2015, 137, 499-507.

2013

Xue, W. ; Kennepohl, P. ; Ruddick, J. N. R. Quantification Of Mobilized Copper(Ii) Levels In Micronized Copper-Treated Wood By Electron Paramagnetic Resonance (Epr) Spectroscopy. Holzforschung 2013, in press, 1–9.
Xue, W. ; Kennepohl, P. ; Ruddick, J. N. R. Quantification Of Mobilized Copper(Ii) Levels In Micronized Copper-Treated Wood By Electron Paramagnetic Resonance (Epr) Spectroscopy. HOLZFORSCHUNG 2013, 67, 815-823.
Chen, P. ; Gamelin, D. R. ; Kennepohl, P. Preface. Coord. Chem. Rev. 2013, 257, 1–2.
Keske, E. C. ; Zenkina, O. V. ; Asadi, A. ; Sun, H. ; Praetorius, J. M. ; Allen, D. P. ; Covelli, D. ; Patrick, B. O. ; Wang, R. ; Kennepohl, P. ; James, B. R. ; Crudden, C. M. Dioxygen Adducts Of Rhodium N-Heterocyclic Carbene Complexes. Dalton Trans. 2013, 42, 7414–23.

2012

Xue, W. ; Kennepohl, P. ; Ruddick, J. N. R. Investigation Of Copper Solubilization And Reaction In Micronized Copper Treated Wood By Electron Paramagnetic Resonance ( Epr ) Spectroscopy. Holzforschung 2012, 66, 889–895.
Cipot-Wechsler, J. ; Covelli, D. ; Praetorius, J. M. ; Hearns, N. ; Zenkina, O. V. ; Keske, E. C. ; Wang, R. ; Kennepohl, P. ; Crudden, C. M. Synthesis And Characterization Of Cationic Rhodium Peroxo Complexes. Organometallics 2012, 31, 7306–7315.
Rueda-Becerril, M. ; Sazepin, C. Chatalova; Leung, J. Cho Tak; Okbinoglu, T. ; Kennepohl, P. ; Paquin, J. - F. ; Sammis, G. M. Fluorine Transfer To Alkyl Radicals. J. Am. Chem. Soc. 2012, 134, 4026–9.

2011

Martin-Diaconescu, V. ; Perepichka, I. ; D Bohle, S. ; Kennepohl, P. Electronic Structure Of S -Nitrosothiols From Sulfur K-Edge X-Ray Absorption Spectroscopy. Can. J. Chem. 2011, 89, 93–97.

2010

Delgado-Jaime, M. Ulises; Kennepohl, P. Development And Exploration Of A New Methodology For The Fitting And Analysis Of Xas Data. Journal of synchrotron radiation 2010, 17, 119–28.
Delgado-Jaime, M. Ulises; Mewis, C. Philip; Kennepohl, P. Blueprint Xas: A Matlab-Based Toolbox For The Fitting And Analysis Of Xas Spectra. J. Syncr. Rad. 2010, 17, 132–7.

2009

Karunakaran-Datt, A. ; Kennepohl, P. Redox Photochemistry Of Methionine By Sulfur K-Edge X-Ray Absorption Spectroscopy: Potential Implications For Cataract Formation. J. Am. Chem. Soc. 2009, 131, 3577–82.
Bates, J. €I. ; Kennepohl, P. ; Gates, D. P. Abnormal Reactivity Of An N-Heterocyclic Carbene (Nhc) With A Phosphaalkene: A Route To A 4-Phosphino-Substituted Nhc. Angew. Chem. Int. Ed. 2009, 48, 9844–9847.
Kennepohl, P. ; Wasinger, E. C. ; George, S. DeBeer X-Ray Spectroscopic Approaches To The Investigation And Characterization Of Photochemical Processes. J. Syncr. Rad. 2009, 16, 484–8.
Martin-Diaconescu, V. ; Kennepohl, P. Effects Of Hyperconjugation On The Electronic Structure And Photoreactivity Of Organic Sulfonyl Chlorides. Inorg. Chem. 2009, 48, 1038–44.
Sriskandakumar, T. ; Petzold, H. ; Bruijnincx, P. C. A. ; Habtemariam, A. ; Sadler, P. J. ; Kennepohl, P. Influence Of Oxygenation On The Reactivity Of Ruthenium-Thiolato Bonds In Arene Anticancer Complexes: Insights From Xas And Dft. J. Am. Chem. Soc. 2009, 131, 13355–61.

2008

Praetorius, J. M. ; Allen, D. P. ; Wang, R. ; Webb, J. D. ; Grein, F. ; Kennepohl, P. ; Crudden, C. M. N-Heterocyclic Carbene Complexes Of Rh: Reaction With Dioxygen Without Oxidation. J. Am. Chem. Soc. 2008, 130, 3724–5.
Getty, K. ; Delgado-Jaime, M. Ulises; Kennepohl, P. Assignment Of Pre-Edge Features In The Ru K-Edge X-Ray Absorption Spectra Of Organometallic Ruthenium Complexes. Inorg. Chim. Acta 2008, 361, 1059.

2007

Martin-Diaconescu, V. ; Kennepohl, P. Sulfur K-Edge Xas As A Probe Of Sulfur-Centered Radical Intermediates. J. Am. Chem. Soc. 2007, 129, 3034–5.
Getty, K. ; Delgado-Jaime, M. Ulises; Kennepohl, P. An Electronic Rationale For Observed Initiation Rates In Ruthenium-Mediated Olefin Metathesis: Charge Donation In Phosphine And N-Heterocyclic Carbene Ligands. J. Am. Chem. Soc. 2007, 129, 15774–6.
Gilroy, J. B. ; McKinnon, S. D. J. ; Kennepohl, P. ; Zsombor, M. S. ; Ferguson, M. J. ; Thompson, L. K. ; Hicks, R. G. Probing Electronic Communication In Stable Benzene-Bridged Verdazyl Diradicals. J. Org. Chem. 2007, 72, 8062–8069.

2006

Delgado-Jaime, M. Ulises; Conrad, J. C. ; Fogg, D. E. ; Kennepohl, P. X-Ray Absorption Methods For The Determination Of Ru–Cl Bond Covalency In Olefin Metathesis Catalysts: On The Normalization Of Chlorine K-Edges In Ruthenium Complexes. Inorg. Chim. Acta 2006, 359, 3042–3047.

2005

Kennepohl, P. ; Neese, F. ; Schweitzer, D. ; Jackson, H. L. ; Kovacs, J. A. ; Solomon, E. I. Spectroscopy Of Non-Heme Iron Thiolate Complexes: Insight Into The Electronic Structure Of The Low-Spin Active Site Of Nitrile Hydratase. Inorg. Chem. 2005, 44, 1826–36.
Solomon, E. I. ; Basumallick, L. ; Chen, P. ; Kennepohl, P. Variable Energy Photoelectron Spectroscopy: Electronic Structure And Electronic Relaxation. Coord. Chem. Rev. 2005, 249, 229–253.

2004

Funk, T. ; Kennepohl, P. ; Di Bilio, A. J. ; Wehbi, Wa; Young, A. T. ; Friedrich, S. ; Arenholz, E. ; Gray, H. B. ; Cramer, S. P. X-Ray Magnetic Circular Dichroism Of Pseudomonas Aeruginosa Nickel(Ii) Azurin. J. Am. Chem. Soc. 2004, 126, 5859–66.

2003

Kennepohl, P. ; Solomon, E. I. Electronic Structure Contributions To Electron-Transfer Reactivity In Iron-Sulfur Active Sites: 1. Photoelectron Spectroscopic Determination Of Electronic Relaxation. Inorg. Chem. 2003, 42, 679–88.
Kennepohl, P. ; Solomon, E. I. Electronic Structure Contributions To Electron-Transfer Reactivity In Iron-Sulfur Active Sites: 2. Reduction Potentials. Inorg. Chem. 2003, 42, 689–95.
Kennepohl, P. ; Solomon, E. I. Electronic Structure Contributions To Electron-Transfer Reactivity In Iron-Sulfur Active Sites: 3. Kinetics Of Electron Transfer. Inorg. Chem. 2003, 42, 696–708.

1997

Westre, T. E. ; Kennepohl, P. ; DeWitt, J. G. ; Hedman, B. ; Hodgson, K. O. ; Solomon, E. I. A Multiplet Analysis Of Fe K-Edge 1S → 3D Pre-Edge Features Of Iron Complexes. J. Am. Chem. Soc. 1997, 119, 6297–6314.

1996

Holm, R. H. ; Kennepohl, P. ; Solomon, E. I. Structural And Functional Aspects Of Metal Sites In Biology. Chem. Rev. 1996, 96, 2239–2314.