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Construction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations

TitleConstruction of protected hydroxylated pyrrolidines using nitrogen-centered radical cyclizations
Publication TypeJournal Article
Year of Publication2009
AuthorsZhai, HM, Zlotorzynska, M, Sammis, G
JournalChemical Communications
Pagination5716-5718
Type of ArticleArticle
ISBN Number1359-7345
Keywords1, 4-DIDEOXY-1, 4-IMINO-L-RIBITOL, ADDITIONS, AMINYL RADICALS, GENERATION, glycosidase, inhibitors, NATURAL OCCURRENCE, ring expansion, ROUTE, STRAIGHTFORWARD SYNTHESIS, THERAPEUTIC APPLICATIONS
Abstract

Nitrogen-centered radical cyclizations onto silyl enol ethers were utilized for the syntheses of protected polyhydroxylated pyrrolidines 2-hydroxymethyl-3-hydroxypyrrolidine and 1,4-dideoxy-1,4-imino-L-ribitol.

URL<Go to ISI>://000270115300013