Our Department

Employment

 

Research Associate Position - Novel Lipids

The candidate will be responsible for designing and executing the synthesis of novel lipids for the formulation of therapeutic nucleic acids in lipid nanoparticulate (LNP) form.  In the process, the person must be able to interact effectively with experts in biological, microfluidic, and formulation science.

The candidate must: have a Ph.D. in chemistry with specialization in organic synthesis, provide evidence of productivity in research, and possess excellent verbal and written communication skills. Postdoctoral experience is desirable.

The candidate must have extensive experience in the chemical synthesis of unnatural lipids of the type currently used in LNP formulations of siRNA and other nucleic acids. Experience in synthetic heterocyclic chemistry, organometallic and coordination chemistry, peptide synthesis, and handling anionic phosphorus compounds (phosphates, phosphonates, phosphinates) is highly desirable. Excellent knowledge of state-of-the-art spectroscopic techniques and separation methods is a must.

The anticipated start date is July 1st, 2020.

How to Apply:

The closing date for all applications is March 31st, 2020. Review of the applications will start on March 2nd, 2020, and will continue until the position is filled.

Applications must be directed by e-mail to Prof. Marco A. Ciufolini, ciufi@chem.ubc.ca

UBC hires on the basis of merit and is strongly committed to equity and diversity within its community. We especially welcome applications from visible minority group members, women, Aboriginal persons, persons with disabilities, persons of minority sexual orientations and gender identities, and others with the skills and knowledge to productively engage with diverse communities.

Canadian citizens and permanent residents will be given priority

 

 

Research Associate Position in Red Blood Cell modification

The laboratory of Dr. Stephen G. Withers in the Department of Chemistry at the University of British Columbia in Vancouver is looking for a Research Associate to fill a position starting in the fall of 2020. The anticipated start date is September 22nd, 2020. The lab is located in a well-equipped research facility that provides a stimulating international and multidisciplinary research environment.

The position is focused on discovery of novel glycoside hydrolases in metagenomic libraries for the modification of surface antigens on red blood cells and the engineering of those for higher affinities and efficacies. Another second focus of the position is on the development of microfluidic screening systems. A third focus is on the collaborative analysis of the immune tolerance of the converted red blood cells. The successful candidate is expected to have completed their PhD and at least four years of postdoctoral research experience. The successful candidate must have demonstrated research experience in both metagenomics and glycobiology. Specifically, the candidate must have demonstrated experience with (1) generation of metagenomic fosmid and small insert libraries; (2) functional metagenomic screening in plate-based and microfluidic systems; (3) metagenomic hit validation and CAZyme classification; (4) protein expression, purification and biochemical characterization of glycoside hydrolases, glycosyltransferases and deacetylases; (5) chemoenzymatic synthesis of complex oligosaccharides such as the A and B blood antigen substrates; (6) handling, modification and molecular typing of RBCs. Demonstrated experience must be documented with first-author publications in impact-factor (>4) journals. The successful candidate must have demonstrated experience in the preparation of research proposals for funding agencies and patent applications. 

How to Apply:

Applications should send by email to hrfacilities@chem.ubc.ca and include a Curriculum Vitae and a Letter of Motivation. Please include “Research Associate Position in RBC modification” in the email subject line; incorrectly addressed applications will not be considered. Please indicate your legal status to work in Canada. The salary will be commensurate with qualifications and experience. The position is available starting fall 2020. Applications will be reviewed after March 6, 2020 and the position will remain open until filled.

Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.

All qualified candidates are encouraged to apply; however, Canadians and permanent residents of Canada will be given priority.