Intermolecular Misfolding Captured in Parallelly Organized Titin
The Li Group's exciting discovery reveals that when titin Ig domains are arranged in parallel, just like their organization within muscle sarcomeres, they can misfold into a stable intermolecular domain-swapped state, which is both thermally and mechanically stable—offering new insights into how this unique misfolding could play an important role in the structure and elasticity of muscle.
Congratulations to Sabrina Scott, a well-deserved recipient of the Inflection Award! Inflection is the first-ever awards program dedicated to identifying and empowering the young...