Electrolytic deuteration of unsaturated bonds without using D2

Site-selective deuteration of C–H bonds increases the lifetime and efficacy of drug molecules. Although effective methods to form C(sp2)–D bonds are known, processes for making C(sp3)–D bonds often have low site selectivity, require expensive and unrecoverable D2 gas, or use stoichiometric reagents. Here we report cost-efficient and site-selective reductive deuteration using a tandem electrochemical chemical palladium membrane reactor. This architecture mediates the chemical reaction of deuterium atoms (derived from reusable D2O in an electrochemical compartment) with alkynes, aldehydes...


Aug 25 2020 - 9:00am to 12:00pm
Andy Tran
UBC Chemistry (MacLachlan Group)
Aug 26 2020 - 9:00am to 12:00pm
Maxim Epifanov
UBC Chemistry (Sammis Group)
Sep 8 2020 - 12:30pm to 3:30pm
Thomas Malig
UBC Chemistry (Hein Group)


Congratulations to Kudzi Nyamayaro!

PhD candidate, Kudzi Nyamayaro, has been awarded the Du Pont Canada Fellowship in pulp and paper. The Du Pont Canada Fellowship in pulp and paper has been endowed by Du Pont Canada Inc and the province of British Columbia. The award is offered to...

Congratulations to David Perrin!

Dr. David Perrin has been funded by the CIHR (Canadian Institutes of Health Research) for his research into the development of non-toxic, drug-like products that can intercept the COVID virus. 

The Government of Canada is providing the...