Interrogating the thionium hydrogen bond as a noncovalent stereocontrolling interaction in chiral phosphate catalysis

CH⋯O bonds are a privileged noncovalent interaction determining the energies and geometries of a large number of structures. In catalytic settings, these are invoked as a decisive feature controlling many asymmetric transformations involving aldehydes. However, little is known about their stereochemical role when the interaction involves other substrate types. We report the results of computations that show for the first time thionium hydrogen bonds to be an important noncovalent interaction in asymmetric catalysis. As a validating case study, we explored an asymmetric Pummerer...


Feb 7 2023 - 12:45pm to 2:00pm
Dr. Katherine S. Elvira
Department of Chemistry, University of Victoria
Feb 14 2023 - 12:45pm to 2:00pm
Dr. Erin R. Johnson
Departments of Chemistry and Physics & Atmospheric Science, Dalhousie University | MacDowell Lecture


Paul Heine receives 3rd place at the AMS 23rd Conference on Air-Sea

Congratulations to Paul Heine, PhD student (Nadine Borduas-Dedekind group), who has received 3rd place in the AMS 23rd Conference student poster presentation competition...

Dr. Miguel Romero Receives the Alumni Builder Award

Congratulations to Dr. Miguel A. Romero who is a recipient of the 2022-23 Alumni Builder Award!

Created in 2017 as part of the 100th year of alumni UBC, the Alumni Builder Awards recognize a cross-section of alumni representing both...