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Absolute configuration of the antiinflamatory sponge natural product contignasterol

TitleAbsolute configuration of the antiinflamatory sponge natural product contignasterol
Publication TypeJournal Article
Year of Publication2002
AuthorsYang, L, Andersen, RJ
JournalJournal of Natural Products
Volume65
Pagination1924-1926
Date PublishedDec
Type of ArticleArticle
ISBN Number0163-3864
KeywordsHISTAMINE-RELEASE, MARINE, MAST-CELLS, XESTOBERGSTEROL-A, XESTOSPONGIA-BERGQUISTIA
Abstract

Chiral auxiliary NMR analysis with C-22 (R/S)-MPA and (R/S)-MTPA esters has been used to demonstrate that the absolute configuration in the side chain of the antiinflammatory sponge metabolite contignasterol (1) is 22R, 24R.

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