|Title||Anti-Markovnikov intermolecular hydroamination: A bis(amidate) titanium precatalyst for the preparation of reactive aldimines|
|Publication Type||Journal Article|
|Year of Publication||2003|
|Authors||Zhang, Z, Schafer, LL|
|Type of Article||Article|
|Keywords||ALKENES, CATALYTIC HYDROAMINATION, COMPLEXES, LIGAND, SCOPE, TERMINAL ALKYNES|
A bulky bis(N-2’,6’-diisopropylphenyi(phenyl)-amidate)titanium-bis(diethylamido) complex was identified as a highly active and regloselective precatalyst for the anti-Markovnikov hydroamination of a wide range of terminal alkyl alkynes; with alkylamines. This titanium complex was fully characterized, including its X-ray crystal structure. The reactive aldimine products generated have been further elaborated using one-pot procedures to give substituted amines, aidehydes, and the isoquinoline framework.
|URL||<Go to ISI>://000186728600052|