Research & Teaching Faculty

  1. Research & Teaching Faculty
  2. Department Publications
  3. Antimitotic diterpenoids from Erythropodium caribaeorum: isolation artifacts and putative biosynthetic intermediates

Antimitotic diterpenoids from Erythropodium caribaeorum: isolation artifacts and putative biosynthetic intermediates

TitleAntimitotic diterpenoids from Erythropodium caribaeorum: isolation artifacts and putative biosynthetic intermediates
Publication TypeJournal Article
Year of Publication2001
AuthorsBritton, R, Roberge, M, Berisch, H, Andersen, RJ
JournalTetrahedron Letters
Volume42
Pagination2953-2956
Date PublishedApr
Type of ArticleArticle
ISBN Number0040-4039
KeywordsELEUTHEROBIN, PACLITAXEL, SARCODICTYIN-A
Abstract

Two new natural products, caribaeorane (12) and 15-hydroxycaribaeorane (11), have been identified in Erythropodium caribaeorum extracts by isolation of their C-4 methylketals 10 and 9. It has been demonstrated that eleutherobin (1) is an isolation artifact. A proposal for the late stages of the biosynthetic pathway to the E. calibaeorum antimitotic diterpenoids is presented. (C) 2001 Published by Elsevier Science Ltd.
URL<Go to ISI>://000168048900007