| Title | Asymmetrical emitter geometries for increased range of stable electrospray flow rates. |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | E. Maxwell, J, Zhong, X, Chen, DDY |
| Journal | Analytical Chemistry (Washington, DC, United States) |
| Volume | 82 |
| Pagination | 8377 - 8381 |
| Date Published | 2010/// |
| ISBN Number | 0003-2700 |
| Keywords | asym emitter geometry electrospray flow rate increase mass spectrometer, capillary electrophoresis mass spectrometer interface asym emitter geometry, liq chromatograph mass spectrometer interface asym emitter geometry |
| Abstract | Because elec. field distribution is detd. by emitter size and shape, sprayer tip geometry dets. the optimum liq. flow rate that can be processed by the electrospray ionization interface. Elec. field is the highest at the sharpest edge of an electrode; therefore, for a beveled tip, the field is highest at the very tip, and for a conventional sym. tapered tip, the field is the highest around the rim of the electrode. Electrospray performance as a function of flow rate was studied using both continuous infusion and peak-based anal. The sharpest sym. emitter gave the most stable electrospray ionization (ESI) at flow rates <=0.10 μL/min, while beveled emitters provided significantly better performance at expanded flow rates up to 1 μL/min. The use of beveled emitters offers the potential for increased versatility in electrospray ionization interfaces. [on SciFinder(R)] |
