Title | An atmospheric pressure ion lens that improves nebulizer assisted electrospray ion sources |
Publication Type | Journal Article |
Year of Publication | 2002 |
Authors | Schneider, BB, Douglas, DJ, Chen, DDY |
Journal | Journal of the American Society for Mass Spectrometry |
Volume | 13 |
Pagination | 906-913 |
Date Published | Aug |
Type of Article | Article |
ISBN Number | 1044-0305 |
Keywords | CAPILLARY-ZONE-ELECTROPHORESIS, DISSOCIATION, EVAPORATION, IDENTIFICATION, INDUCED, INTERFACE, IONIZATION MASS-SPECTROMETRY, JUNCTION, MECHANISM, PROTEIN-ANALYSIS, SHEATHLESS |
Abstract | An atmospheric pressure ion lens improves the performance and ease of use of a nebulizer assisted electrospray (ion spray) ion source. The lens is comprised of an oblong-shaped stainless steel ring attached to an external high voltage power supply. The lens is located near the tip of the conductive sprayer, and is maintained at a potential less than that of the sprayer. The ion lens improves the shape of the equipotential lines in the vicinity of the sprayer tip. This lens gives approximately a 2-fold reduction in the signal RSD, a 2-fold increase in the ion signal, an increase in the number of multiply charged ions, and a much broader range of usable sprayer positions. (C) 2002 American Society for Mass Spectrometry. |
URL | <Go to ISI>://000177704600002 |
