Title | An avenue to the sordarin core adaptable to analog synthesis |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Liang, H, Schule, A, Vors, JP, Ciufolini, MA |
Journal | Organic Letters |
Volume | 9 |
Pagination | 4119-4122 |
Date Published | Oct |
ISBN Number | 1523-7060 |
Abstract | We describe a synthesis of ketones 3 (X = O-R or CN; Y = H or alkyl), which are useful building blocks for the preparation of analogs of the potent antifungal agent sordarin, 1. Congeners of 1 constructed from 3 should permit detailed SAR investigations of the terpenoid core of the natural product. |
URL | <Go to ISI>://000249987200009 |