| Title | Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Linington, RG, Robertson, M, Gauthier, A, Finlay, BB, MacMillan, JB, Molinski, TF, Van Soest, R, Andersen, RJ |
| Journal | Journal of Natural Products |
| Volume | 69 |
| Pagination | 173-177 |
| Date Published | Feb |
| Type of Article | Article |
| ISBN Number | 0163-3864 |
| Keywords | PROTEIN SECRETION, SYSTEMS |
| Abstract | A screening pro-rain aimed at discovering inhibitors of the bacterial type III secretion system identified the MeOH extract of the Caribbean sponge Caminus sphaeroconia as an active hit in the initial assay. Bioassay-guided fractionation of the crude extract. led to the isolation of caminosides A (1) to D (4), a family of antimicrobial glycolipids. The structures of the three new caminosides B (2) to D (4) have been elucidated by spectroscopic analysis. |
| URL | <Go to ISI>://000235943400001 |
