|Title||Direct C-F Bond Formation Using Photoredox Catalysis|
|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||Rueda-Becerril, M, Mahe, O, Drouin, M, Majewski, MB, West, JG, Wolf, MO, Sammis, GM, Paquin, J-F|
|Journal||JOURNAL OF THE AMERICAN CHEMICAL SOCIETY|
|Date Published||FEB 12|
We have developed the first example of a photoredox catalytic method for the formation of carbon-fluorine (C-F) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the (MLCT)-M-3 (triplet metal-to-ligand charge transfer) state of Ru(bpy)(3)(2+) to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.