| Title | DMAP Promoted Tandem Addition Reactions Forming Substituted Tetrahydroxanthones |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Castillo-Contreras, EB, Dake, GR |
| Journal | ORGANIC LETTERS |
| Volume | 16 |
| Pagination | 1642-1645 |
| Date Published | MAR 21 |
| ISSN | 1523-7060 |
| Abstract | Substituted tetrahydroxanthones are constructed using a DMAP-promoted tandem nucleophilic addition process. The reaction yields range from 39% to 73%. Disubstituted tetrahydroxanthones are generated as a similar to 2.3:1 mixture of diastereomers favoring the formation of the trans-isomer. |
| DOI | 10.1021/ol5002945 |