Title | DMAP Promoted Tandem Addition Reactions Forming Substituted Tetrahydroxanthones |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Castillo-Contreras, EB, Dake, GR |
Journal | ORGANIC LETTERS |
Volume | 16 |
Pagination | 1642-1645 |
Date Published | MAR 21 |
ISSN | 1523-7060 |
Abstract | Substituted tetrahydroxanthones are constructed using a DMAP-promoted tandem nucleophilic addition process. The reaction yields range from 39% to 73%. Disubstituted tetrahydroxanthones are generated as a similar to 2.3:1 mixture of diastereomers favoring the formation of the trans-isomer. |
DOI | 10.1021/ol5002945 |
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