| Title | Escherichia coli glucuronylsynthase: An engineered enzyme for the synthesis of beta-glucuronides |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Wilkinson, SM, Liew, CW, Mackay, JP, Salleh, HM, Withers, SG, McLeod, MD |
| Journal | ORGANIC LETTERS |
| Volume | 10 |
| Pagination | 1585-1588 |
| Date Published | APR 17 |
| ISSN | 1523-7060 |
| Abstract | The glycosynthase derived from E coli beta-glucuronidase catalyzes the glucuronylation of a range of primary, secondary, and aryl alcohols with moderate to excellent yields. The procedure provides an efficient, stereoselective, and scalable single-step synthesis of 6-glucuronides under mild conditions. |
| DOI | 10.1021/ol8002767 |
