| Title | Hydroaminoalkylation: Early-Transition-Metal-Catalyzed alpha-Alkylation of Amines |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Chong, E, Garcia, P, Schafer, LL |
| Journal | Synthesis-Stuttgart |
| Volume | 46 |
| Pagination | 2884-2896 |
| Date Published | NOV |
| ISSN | 0039-7881 |
| Abstract | The recent development and progress of early-transition-metal-catalyzed C-H alkylation adjacent to nitrogen of unprotected amines with alkenes are summarized. Group 4 and 5 metal complexes are very effective for hydroaminoalkylation catalysis, an emerging atom-economic C(sp(3))-C(sp(3)) bond formation strategy. 1Introduction 2Group 4 Hydroaminoalkylation Catalysis 2.1Intramolecular Hydroaminoalkylation 2.2Intermolecular Hydroaminoalkylation 3Group 5 Hydroaminoalkylation Catalysis 4Conclusions and Outlook |
| DOI | 10.1055/s-0034-1379216 |
