Title | Isoarenarol, a new protein kinase inhibitor from the marine sponge Dysidea arenaria |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Yoo, HD, Leung, D, Sanghara, J, Daley, D, Van Soest, R, Andersen, RJ |
Journal | Pharmaceutical Biology |
Volume | 41 |
Pagination | 223-225 |
Date Published | Jun |
Type of Article | Article |
ISBN Number | 1388-0209 |
Keywords | AVAROL, hydroquinone, kinase inhibitor, marine sponge, Papua New Guinea, sesquiterpene |
Abstract | The novel sesquiterpene hydroquinone isoarenarol (1) and the known compound arenarol (2) were isolated from extracts of the marine sponge Dysidea arenaria Bergquist as part of a search for new protein kinase inhibitors. Both 1 and 2 showed potent and selective protein kinase inhibition in vitro. |
URL | <Go to ISI>://000184898600001 |