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Metal complexes in medicinal chemistry: new vistas and challenges in drug design

TitleMetal complexes in medicinal chemistry: new vistas and challenges in drug design
Publication TypeJournal Article
Year of Publication2006
AuthorsThompson, KH, Orvig, C
JournalDalton Transactions
Pagination761-764
Date PublishedFeb
Type of ArticleArticle
ISBN Number1477-9226
KeywordsAGENTS, BINDING CONSTANTS, BIS(MALTOLATO)OXOVANADIUM(IV), GLUCOSE, HUMAN-SERUM TRANSFERRIN, MODULATION, therapy, TRANSPORT
Abstract

An overview is presented of selected metal-bases! pharmaceuticals, either diagnostic or therapeutic, with emphasis on specific attributes and in vivo interactions of these compounds relevant to their use in medicinal applications. Both the advantages and the challenges of this approach are outlined, with possibilities for future developments accentuated.

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