Title | Molecular mechanics-assisted crystal engineering of solid state photoreactions: application to the Yang photocyclization of alpha-1-norbornylacetophenone derivatives |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Botoshansky, M, Braga, D, Kaftory, M, Maini, L, Patrick, BO, Scheffer, JR, Wang, KY |
Journal | Tetrahedron Letters |
Volume | 46 |
Pagination | 1141-1144 |
Date Published | Feb |
Type of Article | Article |
ISBN Number | 0040-4039 |
Keywords | ASYMMETRIC INDUCTION, crystal engineering, GEOMETRIC REQUIREMENTS, II REACTION, ionic chiral auxiliaries, REACTIVITY, solid state photochemistry, X-RAY CRYSTALLOGRAPHY, Yang photocyclization |
Abstract | Based on molecular mechanics, Yang photocyclization of alpha-1-norbornylacetophenone derivatives in the crystalline state was engineered through methylation adjacent to the carbonyl group, thus changing the conformation in the crystal and leading to enhanced diastereo- and enantioselectivity. (C) 2004 Elsevier Ltd. All rights reserved. |
URL | <Go to ISI>://000226846800021 |
