| Title | MOLECULAR PROBES Getting lucky in the lysosome |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Goddard-Borger, ED, Wennekes, T, Withers, SG |
| Journal | NATURE CHEMICAL BIOLOGY |
| Volume | 6 |
| Pagination | 881-883 |
| Date Published | DEC |
| ISSN | 1552-4450 |
| Abstract | Conjugation of a known, mechanism-based glycosidase inhibitor to sensitive fluorophores yielded unexpectedly potent and selective probes for quantifying active lysosomal glucocerebrosidase. These conjugates could prove to be invaluable tools for diagnosing and studying Gaucher disease. |
| DOI | 10.1038/nchembio.470 |
