| Title | MOTUPORIN, A POTENT PROTEIN PHOSPHATASE INHIBITOR ISOLATED FROM THE PAPUA-NEW-GUINEA SPONGE THEONELLA-SWINHOEI GRAY |
| Publication Type | Journal Article |
| Year of Publication | 1992 |
| Authors | De Silva, ED, Williams, DE, Andersen, RJ, Klix, H, Holmes, CFB, Allen, TM |
| Journal | Tetrahedron Letters |
| Volume | 33 |
| Pagination | 1561-1564 |
| Date Published | Mar |
| Type of Article | Article |
| ISBN Number | 0040-4039 |
| Keywords | BIOACTIVE MARINE METABOLITES, MICROCYSTIS-AERUGINOSA, PEPTIDE, TOXIN |
| Abstract | Motuporin (1), a cyclic pentapeptide that is a potent protein phosphatase-1 inhibitor and cytotoxin, has been isolated from the marine sponge Theonella swinhoei collected in Papua New Guinea. The structure of motuporin was elucidated by spectroscopic analysis and chemical degradation. |
| URL | <Go to ISI>://A1992HJ78400009 |
