Date:
Wednesday, November 20, 2024 - 17:00 to 18:00
Speaker:
Desiree Fiaccabrino
Affiliation:
Department of Chemistry, The University of British Columbia - Orvig/Schaffer (TRIUMF)/Hudson Group
Event Category:
IMDG - Inorganic & Materials Discussion Group
Location:
Chemistry D300
Abstract:
Nuclear medicine is a multidisciplinary field that applies radioactive nuclides for disease diagnosis, staging, treatment, and research. Many of the most promising diagnostic and therapeutic radioisotopes are metal ions, highlighting the importance of developing chelating ligands capable of coordinating a wide range of radiometals. In this seminar, I will present ongoing work on the development of chelators for several exotic radioactive metals relevant to nuclear medicine, specifically Actinium-225, Thorium-227, Bismuth-213, Lead-203 and Terbium-155/161. The focus will be on the characterization of metal complexes using techniques such as NMR, DFT, and thermodynamic solution studies, along with radiolabeling studies.