Title | Bogorol A produced in culture by a marine Bacillus sp reveals a novel template for cationic peptide antibiotics |
Publication Type | Journal Article |
Year of Publication | 2001 |
Authors | Barsby, T, Kelly, MT, Gagne, SM, Andersen, RJ |
Journal | Organic Letters |
Volume | 3 |
Pagination | 437-440 |
Date Published | Feb |
Type of Article | Article |
ISBN Number | 1523-7060 |
Keywords | BACTERIUM, DEFENSINS, HELIX, resistance |
Abstract | [GRAPHICS] Bogorol A (1), a novel peptide antibiotic active against MRSA and VRE, has been isolated from cultures of a marine Bacillus sp, collected in Papua New Guinea, The structure of bogorol A was elucidated by a combination of spectroscopic analyses and chemical degradation. Bogorol A illustrates a new structural template for "cationic peptide antibiotics". |
URL | <Go to ISI>://000166778800032 |
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