Title | Construction of azaspirocyclic ketones through alpha-hydroxyiminium ion or alpha-siloxy epoxide semipinacol rearrangements |
Publication Type | Journal Article |
Year of Publication | 2001 |
Authors | Fenster, MDB, Patrick, BO, Dake, GR |
Journal | Organic Letters |
Volume | 3 |
Pagination | 2109-2112 |
Date Published | Jun |
Type of Article | Article |
ISBN Number | 1523-7060 |
Keywords | ACIDS, ALDOL PROCESS, ALKALOIDS, HALICHLORINE |
Abstract | [GRAPHICS] Semipinacol-type rearrangements to produce azaspirocyclic ketones are presented. The yields and stereoselectivities of these reactions range from 67-94% yield and 2.8:1 to 1:0 diastereoselectivity, respectively. |
URL | <Go to ISI>://000169487700037 |
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