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O-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides

TitleO-Glycoligases, a new category of glycoside bond-forming mutant glycosidases, catalyse facile syntheses of isoprimeverosides
Publication TypeJournal Article
Year of Publication2010
AuthorsKim, Y-W, Zhang, R, Chen, H, Withers, SG
JournalCHEMICAL COMMUNICATIONS
Volume46
Pagination8725-8727
ISSN1359-7345
Abstract

A mutant alpha-xylosidase that lacks its catalytic acid/base residue efficiently catalyses the synthesis of O-linked isoprimeverosides (Xyl-alpha-1,6GlcOR) in near quantitative yields.

DOI10.1039/c0cc03168b